In today's era, transportation has become an integral and indispensable part of daily life. Traffic safety is a top priority worldwide to reduce accidents and damage to both people and property. Research and development of safety systems are becoming increasingly important, and there has been recent progress in the design of energy-absorbing crash boxes in origami shapes made from Carbon Fiber Reinforced Polymer (CFRP) materials. This study first identifies an optimal origami-shaped crash box geometry made of CFRP, and then systematically investigates the impact of CFRP material parameters (layer orientation angles and thickness) on its energy absorption and collision performance. Using the Taguchi method in design and research, the results show that the box made of CFRP material exhibits approximately 40% higher impact resistance to an aluminum box of the same weight and dimensions. However, CFRP boxes have a maximum crushing force 2.5 times higher than aluminum. Compared to conventional square box structures using aluminum, origami structures with CFRP material also exhibit better energy absorption efficiency and lower maximum crushing force by 118%.