Purpose. This article deals with a three hybrid modeling methods of a virtual skull implants, developed by the author. 3D models of cranial implants are nowadays necessary for the creation of real implants using modern manufacturing technologies. Methods. These methods combine simultaneous usage of three modeling systems (which causes their hybridity): computer tomography system (as a reverse engineering system), surface modeling system and haptic modeling system, and their characteristic modeling methods and techniques. Whereby to common used three different modeling systems we have obtained a synergic effect of the implant shape model quality increasing. Results. The result of using the developed hybrid methods are models of exemplary cranial implants. The common feature of these methods is that the target virtual model of the cranial implant is always well-suited the coastline of bone hole in the skull. Conclusions. The time of developed of the virtual model of any cranial implant using proposed methods is very shorter compared to use of only one of standard 3D systems. Similarly, the amount of modeling work put in is also much smaller than using only one standard 3D system. The article describes hybrid modeling methods developed by the author only.